Cell-Free Total Nucleic Acid-Based Genotyping of Aggressive Lymphoma: Comprehensive Analysis of Gene Fusions and Nucleotide Variants by Next-Generation Sequencing

Cell-Free Total Nucleic Acid-Based Genotyping of Aggressive Lymphoma: Comprehensive Analysis of Gene Fusions and Nucleotide Variants by Next-Generation Sequencing

Chromosomal translocations and pathogenic nucleotide variants both gained special clinical importance in lymphoma diagnostics. Non-invasive genotyping from peripheral blood (PB) circulating free nucleic acid has been effectively used to demonstrate cancer-related nucleotide variants, while gene fusi...

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Bibliographic Details
Main Authors: Attila Mokánszki, Réka Bicskó, Lajos Gergely, Gábor Méhes
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
aggressive lymphoma
liquid biopsy
cell-free nucleic acid
gene fusion
mutation analysis
next-generation sequencing (NGS)
Online Access:https://www.mdpi.com/2072-6694/13/12/3032

Internet

https://www.mdpi.com/2072-6694/13/12/3032

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