Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA(D257A/D257A) mice

Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA(D257A/D257A) mice

Abstract Background Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To improve our understanding of the underlying pathophysi...

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Bibliographic Details
Main Authors: Ariane C. Scheuren, Gommaar D'Hulst, Gisela A. Kuhn, Evi Masschelein, Esther Wehrle, Katrien De Bock, Ralph Müller
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Aging
Osteopenia
Sarcopenia
Osteosarcopenia
mTORC1
in vivo micro‐CT
Online Access:https://doi.org/10.1002/jcsm.12588

Internet

https://doi.org/10.1002/jcsm.12588

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