CDC20 Knockdown and Acidic Microenvironment Collaboratively Promote Tumorigenesis through Inhibiting Autophagy and Apoptosis

The reconstitution of the tumorigenesis process would shed light on the tumor development study and further drug selection strategies. To construct a tumorigenesis model and explore potential mechanism is of great importance. In our study, we observed that CDC20-knockdown cells cultured in acidic en...

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Bibliographic Details
Main Authors: Qingying Gu, Fang Li, Shengfang Ge, Feifei Zhang, Renbing Jia, Xianqun Fan
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300401