Combination of metformin and 9-cis retinoic acid increases apoptosis in C6 glioma stem-like cells

Glioblastoma (GBM) is the most commonly diagnosed type of brain cancer and the leading cause of brain cancer-related death. GBM contains a subpopulation of tumor-propagating glioblastoma stem-like cells that are thought to drive cancer progression and recurrence. Although several clinical trials are...

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Bibliographic Details
Main Authors: Chanchai Songthaveesin, Wanna Sa-nongdej, Tanapol Limboonreung, Sukumal Chongthammakun
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401830080X