CPA-seq reveals small ncRNAs with methylated nucleosides and diverse termini

CPA-seq reveals small ncRNAs with methylated nucleosides and diverse termini

Abstract High-throughput sequencing reveals the complex landscape of small noncoding RNAs (sRNAs). However, it is limited by requiring 5′-monophosphate and 3′-hydroxyl in RNAs for adapter ligation and hindered by methylated nucleosides that interfere with reverse transcription. Here we develop Cap-C...

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Bibliographic Details
Main Authors: Heming Wang, Rong Huang, Ling Li, Junjin Zhu, Zhihong Li, Chao Peng, Xuran Zhuang, Haifan Lin, Shuo Shi, Pengyu Huang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00265-2

Internet

https://doi.org/10.1038/s41421-021-00265-2

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