Premature Adrenarche in Children with Prader-Willi Syndrome Treated with Recombinant Human Growth Hormone Seems to Not Influence the Course of Central Puberty and the Efficacy and Safety of the Therapy

Puberty in children with Prader-Willi syndrome (PWS) is usually delayed and/or incomplete but in some patients premature/early adrenarche is observed. We assessed the premature adrenarche (PA) in PWS patients during the recombinant human growth hormone (rhGH) therapy and influence of PA on the cours...

Full description

Bibliographic Details
Main Authors: Agnieszka Lecka-Ambroziak, Marta Wysocka-Mincewicz, Kamila Marszałek-Dziuba, Agnieszka Rudzka-Kocjan, Mieczysław Szalecki
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/10/10/237