FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function

FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function

Summary: 53BP1 plays a central role in dictating DNA repair choice between non-homologous end joining (NHEJ) and homologous recombination (HR), which is important for the sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis) of BRCA1-deficient cancers. In this study, we show that FOXK1 asso...

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Bibliographic Details
Main Authors: Mengfan Tang, Xu Feng, Guangsheng Pei, Mrinal Srivastava, Chao Wang, Zhen Chen, Siting Li, Huimin Zhang, Zhongming Zhao, Xu Li, Junjie Chen
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720310032

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http://www.sciencedirect.com/science/article/pii/S2211124720310032

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