Preparation and in vitro-in vivo evaluation of intestinal retention pellets of Berberine chloride to enhance hypoglycemic and lipid-lowing efficacy

Berberine chloride (BBR) is a pharmacokinetic profile of drug with poor bioavailability but good therapeutic efficacy, which is closely related to the discovery of BBR intestinal target. The major aim of this paper is to develop BBR intestinal retention type sustained-release pellets and evaluate th...

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Bibliographic Details
Main Authors: Guofei Li, Mingming Zhao, Xianying Su, Lin Song, Limei Zhao
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618306949