Human Platelet Lysate Media Supplement Supports Lentiviral Transduction and Expansion of Human T Lymphocytes While Maintaining Memory Phenotype

Immune cell therapy has emerged as a promising approach to treat malignancies that were up until recently only treated on a palliative basis. Chimeric antigen receptor- (CAR-) modified T lymphocytes (T cells) in particular have proven to be very effective for certain hematological malignancies. The...

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Bibliographic Details
Main Authors: Emanuele Canestrari, Hayley R. Steidinger, Brianna McSwain, Steven J. Charlebois, Christina Tenenhaus Dann
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/3616120