miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome

In humans, the most common genomic disorder is a hemizygous deletion of a 1.5 to 3 Mb region of chromosome 22q11.2. The resultant 22q11.2 deletion syndrome (22q11.2DS) can affect multiple organ systems, and most notably includes cardiac, craniofacial, and neurodevelopmental defects. Individuals wi...

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Bibliographic Details
Main Authors: Linda M Brzustowicz, Anne S Bassett
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00291/full