Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon sequencing

Abstract Background Testing for differential abundance of microbes in disease is a common practice in microbiome studies. Numerous differential abundance (DA) testing methods exist and range from traditional statistical tests to methods designed for microbiome data. Comparison studies of DA testing...

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Bibliographic Details
Main Author: Zachary D. Wallen
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Bioinformatics
Subjects:
16S
Online Access:https://doi.org/10.1186/s12859-021-04193-6