Internalization of Neutrophil-Derived Microvesicles Modulates TNFα-Stimulated Proinflammatory Cytokine Production in Human Fibroblast-Like Synoviocytes

Internalization of Neutrophil-Derived Microvesicles Modulates TNFα-Stimulated Proinflammatory Cytokine Production in Human Fibroblast-Like Synoviocytes

Neutrophil-derived microvesicles (NDMVs) have the potential to exert anti-inflammatory effects. Our study aimed to explore the effects of NDMVs on proinflammatory cytokines expressed by tumor necrosis factor α (TNFα)-stimulated fibroblast-like synoviocytes (FLS). FLS were isolated from the synovium...

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Bibliographic Details
Main Authors: Dong Zhan, Andrew Cross, Helen L. Wright, Robert J. Moots, Steven W. Edwards, Sittisak Honsawek
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
fibroblast-like synoviocytes
neutrophil-derived microvesicles
cytokines
synovitis
osteoarthritis
Online Access:https://www.mdpi.com/1422-0067/22/14/7409

Internet

https://www.mdpi.com/1422-0067/22/14/7409

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