Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair

The cellular cytoskeleton, adhesion receptors, extracellular matrix composition, and their spatial distribution are together fundamental in a cell's balanced mechanical sensing of its environment. We show that, in lung injury, extracellular matrix-integrin interactions are altered and this lead...

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Bibliographic Details
Main Authors: Rehab AlJamal-Naylor, Linda Wilson, Susan McIntyre, Fiona Rossi, Beth Harrison, Mark Marsden, David J. Harrison
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2012/768720