Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair
The cellular cytoskeleton, adhesion receptors, extracellular matrix composition, and their spatial distribution are together fundamental in a cell's balanced mechanical sensing of its environment. We show that, in lung injury, extracellular matrix-integrin interactions are altered and this lead...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Advances in Pharmacological Sciences |
Online Access: | http://dx.doi.org/10.1155/2012/768720 |