Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.

Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.

The presence of cancer stem cells (CSCs) or tumor-initiating cells can lead to cancer recurrence in a permissive cell-microenvironment interplay, promoting invasion in glioblastoma (GBM) and neuroblastoma (NB). Extracellular matrix (ECM) small leucine-rich proteoglycans (SLRPs) play multiple roles i...

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Bibliographic Details
Main Authors: Cristiano Farace, Jaime Antonio Oliver, Consolacion Melguizo, Pablo Alvarez, Pasquale Bandiera, Ana Rosa Rama, Giulia Malaguarnera, Raul Ortiz, Roberto Madeddu, Jose Prados
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4521885?pdf=render

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http://europepmc.org/articles/PMC4521885?pdf=render

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