Drug Crystal-Related Gastrointestinal Complications Involve Crystal-Induced Release of Neutrophil and Monocyte Extracellular Traps

Drug Crystal-Related Gastrointestinal Complications Involve Crystal-Induced Release of Neutrophil and Monocyte Extracellular Traps

Ion-exchange resins are commonly used to manage complications of chronic kidney disease, such as hyperphosphatemia, hyperkalemia, and hypercholesterolemia. Occasionally, these drugs can irritate the gastrointestinal lining and cause life-threatening intestinal necrosis. Currently, the pathophysiolog...

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Bibliographic Details
Main Authors: Tehyung Kim, Sueli de Oliveira Silva Lautenschlager, Qiuyue Ma, Kathrin Eller, Marion Julia Pollheimer, Danielle Lazarin-Bidóia, Celso Vataru Nakamura, Hans-Joachim Anders, Stefanie Steiger
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
sevelamer
polystyrene sulfonate
cholestyramine
patiromer
exchange resin
extracellular traps
Online Access:https://www.mdpi.com/2073-4409/9/11/2481

Internet

https://www.mdpi.com/2073-4409/9/11/2481

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