Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats

Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats

Alcohol use disorder (AUD) is associated with persistent adaptations in the brain that are believed to participate in the long-lasting vulnerability to relapse after abstinence. Cholesterol, the major sterol compound found in the central nervous system (CNS), plays a major role in maintenance of neu...

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Bibliographic Details
Main Authors: Josette Alsebaaly, Emilie Dugast, Laure Favot, Lydia Rabbaa Khabbaz, Marcello Solinas, Nathalie Thiriet
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
alcohol
addiction
cholesterol metabolism
gene expression
neuroadaptations
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00457/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00457/full

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