Physiological and molecular effects of interleukin-18 administration on the mouse kidney

Physiological and molecular effects of interleukin-18 administration on the mouse kidney

Abstract Background The cytokine interleukin-18 was originally identified as an interferon-γ-inducing proinflammatory factor; however, there is increasing evidence to suggest that it has non-immunological effects on physiological functions. We previously investigated the potential pathophysiological...

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Bibliographic Details
Main Authors: Kyosuke Yamanishi, Keiichiro Mukai, Takuya Hashimoto, Kaoru Ikubo, Keiji Nakasho, Yosif El-Darawish, Wen Li, Daisuke Okuzaki, Yuko Watanabe, Tetsu Hayakawa, Hiroshi Nojima, Hiromichi Yamanishi, Haruki Okamura, Hisato Matsunaga
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Translational Medicine
Subjects:
Interleukin-18
Interleukin-18 knockout
Kidney
Clinical translation
Kidney injury
Microarray
Online Access:http://link.springer.com/article/10.1186/s12967-018-1426-6

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http://link.springer.com/article/10.1186/s12967-018-1426-6

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