Hepatitis B e Antigen Induces NKG2A+ Natural Killer Cell Dysfunction via Regulatory T Cell-Derived Interleukin 10 in Chronic Hepatitis B Virus Infection

Hepatitis B e Antigen Induces NKG2A+ Natural Killer Cell Dysfunction via Regulatory T Cell-Derived Interleukin 10 in Chronic Hepatitis B Virus Infection

Although persistent hepatitis B virus (HBV) infection is associated with natural killer (NK) cell dysfunction, it remains obscure whether HBV viral antigens are responsible for NK cell dysfunction in patients with chronic hepatitis B (CHB) infection. In this study, we found that the percentage of NK...

Full description

Bibliographic Details
Main Authors: Qingqing Ma, Xiaoyu Dong, Siyu Liu, Tao Zhong, Dandan Sun, Lu Zong, Changcheng Zhao, Qiong Lu, Min Zhang, Yufeng Gao, Ying Ye, Jun Cheng, Yuanhong Xu, Meijuan Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hepatitis B e antigen
HBV
NK cell
NKG2A
IL-10
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00421/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00421/full

Similar Items