Microbiota Imbalance Contributes to COPD Deterioration by Enhancing IL-17a Production via miR-122 and miR-30a

Microbiota Imbalance Contributes to COPD Deterioration by Enhancing IL-17a Production via miR-122 and miR-30a

The changes of microbiota in lungs could change interleukin-17a (IL-17a) expression by altering microRNAs (miRNAs) profile, thus contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD). In this study, we aimed to study molecular mechanisms’ underlying effect of microbiota im...

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Bibliographic Details
Main Authors: Ke Zhu, Sijing Zhou, Aiqun Xu, Li Sun, Min Li, Huihui Jiang, Binbin Zhang, Daxiong Zeng, Guanghe Fei, Ran Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
COPD
microbiota
miRNA
IL-17a
lactobacillus
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302882

Internet

http://www.sciencedirect.com/science/article/pii/S2162253120302882

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