Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice

Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice

Neurogenesis in the subventricular zone (SVZ) of the adult brain may contribute to tissue repair after brain injuries. Whether SVZ neurogenesis can be upregulated by specific neuronal activity in vivo and promote functional recovery after stroke is largely unknown. Using the spatial and cell type sp...

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Bibliographic Details
Main Authors: Mingke Song, Shan Ping Yu, Osama Mohamad, Wenyuan Cao, Zheng Zachory Wei, Xiaohuan Gu, Michael Qize Jiang, Ling Wei
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Neurobiology of Disease
Subjects:
SVZ neurogenesis
Striatum stimulation
Optogenetics
Glutamatergic neurons
Ischemic stroke
Semi-phasic synaptic regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116302650

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http://www.sciencedirect.com/science/article/pii/S0969996116302650

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