Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy

Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy

The leading cause of death in pulmonary arterial hypertension (PAH) is right ventricular (RV) failure (RVF). Reactive oxygen species (ROS) have been suggested to play a role in the development of RV hypertrophy (RVH) and the transition to RVF. The hydrogen peroxide-generating protein p66shc has been...

Full description

Bibliographic Details
Main Authors: Christine Hirschhäuser, Akylbek Sydykov, Annemarie Wolf, Azadeh Esfandiary, Julia Bornbaum, Hanna Sarah Kutsche, Kerstin Boengler, Natascha Sommer, Rolf Schreckenberg, Klaus-Dieter Schlüter, Norbert Weissmann, Ralph Schermuly, Rainer Schulz
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
reactive oxygen species
cardiac hypertrophy
p66shc
heart failure
Online Access:https://www.mdpi.com/1422-0067/21/24/9339

Internet

https://www.mdpi.com/1422-0067/21/24/9339

Similar Items