Clinical recommendations for the measurement of serum free light chains and the emerging role of heavy/light chain pair analysis in the management of monoclonal gammopathies: When and how to use it?

Clinical recommendations for the measurement of serum free light chains and the emerging role of heavy/light chain pair analysis in the management of monoclonal gammopathies: When and how to use it?

Protein and immunofixation electrophoresis are the laboratory backbone assays for testing multiple myeloma (MM) and related plasma cell proliferative diseases. The secreted monoclonal proteins act as serological tumor markers, and the electrophoretic assays identify monoclonal proteins for diagnosis...

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Bibliographic Details
Main Authors: Juana Jiménez Jiménez, Nuno Miguel Barbosa de Carvalho, Carmen Hernando de Larramendi, Maria Antonia Peñalver Díaz
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Applied Hematology
Subjects:
Amyloid light chain amyloidosis
immunoglobulin′s heavy/light chain pairs
monoclonal gammopathy of uncertain significance
myeloma
serum free light chains
Online Access:http://www.jahjournal.org/article.asp?issn=1658-5127;year=2015;volume=6;issue=2;spage=43;epage=52;aulast=Jiménez

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http://www.jahjournal.org/article.asp?issn=1658-5127;year=2015;volume=6;issue=2;spage=43;epage=52;aulast=Jiménez

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