Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-11082-3 |