Ganglioside Metabolism in a Transgenic Mouse Model of Alzheimer's Disease: Expression of Chol-1α Antigens in the Brain

The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with the biochemical pathology of neurological d...

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Bibliographic Details
Main Authors: Toshio Ariga, Makoto Yanagisawa, Chandramohan Wakade, Susumu Ando, Jerry J Buccafusco, Michael P McDonald, Robert K Yu
Format: Article
Language:English
Published: SAGE Publishing 2010-08-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20100021