Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source.

Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source.

BACKGROUND: Mycobacterium ulcerans, a slow-growing environmental bacterium, is the etiologic agent of Buruli ulcer, a necrotic skin disease. Skin lesions are caused by mycolactone, the main virulence factor of M. ulcerans, with dermonecrotic (destruction of the skin and soft tissues) and immunosuppr...

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Bibliographic Details
Main Authors: Caroline Deshayes, Shiva Kumar Angala, Estelle Marion, Irène Brandli, Jérémie Babonneau, Laurent Preisser, Sara Eyangoh, Yves Delneste, Pierre Legras, Chantal De Chastellier, Timothy P Stinear, Mary Jackson, Laurent Marsollier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3828164?pdf=render

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http://europepmc.org/articles/PMC3828164?pdf=render

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