Mechanistic interpretation of non-coding variants for discovering transcriptional regulators of drug response
Abstract Background Identification of functional non-coding variants and their mechanistic interpretation is a major challenge of modern genomics, especially for precision medicine. Transcription factor (TF) binding profiles and epigenomic landscapes in reference samples allow functional annotation...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-07-01
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| Series: | BMC Biology |
| Online Access: | http://link.springer.com/article/10.1186/s12915-019-0679-8 |