Macropinocytosis in Phagocytes: Regulation of MHC Class-II-Restricted Antigen Presentation in Dendritic Cells

AbstractDendritic cells (DCs) are outstanding antigen presenting cells (APCs) due to their robust ability to internalize extracellular antigens using endocytic processes such as receptor-mediated endocytosis, phagocytosis, and macropinocytosis. Macropinocytosis mediates the non-specific uptake of so...

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Bibliographic Details
Main Authors: Zhenzhen eLiu, Paul A. Roche
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00001/full