The Absence of CYP3A5*3 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects.

The Absence of CYP3A5*3 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects.

Although aromatic anticonvulsants are usually well tolerated, they can cause cutaneous adverse drug reactions in up to 10% of patients. The clinical manifestations of the antiepileptics-induced hypersensitivity reactions (AHR) vary from mild skin rashes to severe cutaneous drug adverse reactions whi...

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Bibliographic Details
Main Authors: Luciana Kase Tanno, Daniel Shikanai Kerr, Bernardo dos Santos, Leda Leme Talib, Célia Yamaguti, Helcio Rodrigues, Wagner Farid Gattaz, Jorge Kalil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546353?pdf=render

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http://europepmc.org/articles/PMC4546353?pdf=render

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