Reshaping of the gastrointestinal microbiome alters atherosclerotic plaque inflammation resolution in mice

Abstract Since alterations in the intestinal microbiota may induce systemic inflammation and polarization of macrophages to the M1 state, the microbiome role in atherosclerosis, an M1-driven disease, requires evaluation. We aimed to determine if antibiotic (Abx) induced alterations to the intestinal...

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Bibliographic Details
Main Authors: Michael S. Garshick, Cyrus Nikain, Michael Tawil, Stephanie Pena, Tessa J. Barrett, Benjamin G. Wu, Zhan Gao, Martin J. Blaser, Edward A. Fisher
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88479-y