The Many Facets of SDF-1α, CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells

The Many Facets of SDF-1α, CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells

Stromal cell-derived factor-1alpha (SDF-1α) has pleiotropic effects on hematopoietic progenitor cells (HPCs). We have monitored podia formation, migration, proliferation, and cell-cell adhesion of human HPC under the influence of SDF-1α, a peptide agonist of CXCR4 (CTCE-0214), a peptide antagonis...

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Bibliographic Details
Main Authors: Anne Faber, Christoph Roderburg, Frederik Wein, Rainer Saffrich, Anja Seckinger, Kerstin Horsch, Anke Diehlmann, Donald Wong, Gary Bridger, Volker Eckstein, Anthony D. Ho, Wolfgang Wagner
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2007/26065

Internet

http://dx.doi.org/10.1155/2007/26065

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