A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity

Abstract Background The current BCG vaccine induces only short-term protection against Mycobacterium tuberculosis (Mtb), suggesting its failure to generate long-lasting memory T cells. Previously, we have demonstrated that a self-adjuvanting peptide of Mtb (L91), successfully generated enduring memo...

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Bibliographic Details
Main Authors: Pradeep K. Rai, Sathi Babu Chodisetti, Weiguang Zeng, Sajid Nadeem, Sudeep K. Maurya, Susanta Pahari, Ashok K. Janmeja, David C. Jackson, Javed N. Agrewala
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Translational Medicine
Subjects:
Vaccine
BCG
L91
TB
Mtb
Th1
Online Access:http://link.springer.com/article/10.1186/s12967-017-1301-x

Internet

http://link.springer.com/article/10.1186/s12967-017-1301-x

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