Dysfunctional Innate Immune Responses and Severe Dengue

Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild self-limiting illness in the majority of individuals. There is emerging evidence that an aberrant immune response in the initial stages of infection lead to severe disease. Many inflammatory cytokines, chemokines,...

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Bibliographic Details
Main Authors: Gathsaurie Neelika Malavige, Chandima Jeewandara, Graham S. Ogg
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.590004/full