Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil Estudo de hepatócitos de rato em cultura primária submetidos a hipóxia e reoxigenação: ação dos citoprotetores prostaglandina E1, superóxido dismutase, alopurinol e verapamil

Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil Estudo de hepatócitos de rato em cultura primária submetidos a hipóxia e reoxigenação: ação dos citoprotetores prostaglandina E1, superóxido dismutase, alopurinol e verapamil

CONTEXT: Exposure of hepatocytes to pathological conditions in a microenvironment of hypoxia and reoxygenation is very frequent in hepatic diseases. Several substances present perspectives for cytoprotective action on hepatocyte submitted to reoxygenation after hypoxia and simple hypoxia. OBJECTIVE:...

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Bibliographic Details
Main Authors: Dahir Ramos de Andrade Jr., Dahir Ramos de Andrade, Sânia Alves dos Santos
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2009-12-01
Series:Arquivos de Gastroenterologia
Subjects:
Hepatócitos
Hipóxia celular
Prostaglandinas E
Superóxido dismutase
Alopurinol
Verapamil
Ratos
Hepatocytes
Cell hypoxia
Prostaglandins E
Superoxide dismutase
Allopurinol
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032009000400016

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032009000400016

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