DNA/RNA transverse current sequencing: Intrinsic structural noise from neighboring bases

Nanopore DNA sequencing via transverse current has emerged as a promising candidate for third-generation sequencing technology. It produces long read lengths which could alleviate problems with assembly errors inherent in current technologies. However, the high error rates of nanopore sequencing hav...

Full description

Bibliographic Details
Main Authors: Jose eAlvarez, Dmitry eSkachkov, Steven eMassey, Alan eKalitsov, Julian eVelev
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
RNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00213/full