Flaxseed Prevents Interferon-alpha Induced Depressive Behavior in Mice: the α-Linolenic Acid is Essential

Background and objectives: Interferon-alpha (IFN-α) is a cytokine with various clinical applications, but it may induce depression by decreasing tryptophan level and producing neuroactive metabolites. Since Linum usitatissimum (flaxseed) is a valuable source for amino acids, α-linolenic acid (ALA),...

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Bibliographic Details
Main Authors: Azadeh Mesripour*, Maryam Almasi
Format: Article
Language:English
Published: Iranian Society of Pharmacognosy 2021-01-01
Series:Research Journal of Pharmacognosy
Subjects:
Online Access:http://www.rjpharmacognosy.ir/article_120236_315a22a9da8862a7b82915c3425c370c.pdf