Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin

<p>Abstract</p> <p>Background</p> <p>Survivin is a unique member of the inhibitor of apoptosis protein (IAP) family in that it exhibits antiapoptotic properties and also promotes the cell cycle and mediates mitosis as a chromosome passenger protein. Survivin is highly e...

Full description

Bibliographic Details
Main Authors: Eisch Amelia, Cremer Harold, Reumers Veerle, Baekelandt Veerle, Moons Michaël, Antonucci Flavia, Cremer Jonathan, DeVriese Astrid, D'Hooge Rudi, Balschun Detlef, Ahmed Tariq, Coremans Vanessa, Lagace Diane, Janssens Tom, Bozzi Yuri, Caleo Matteo, Conway Edward M
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/2