Mycobacterium bovis-BCG vaccination induces specific pulmonary transcriptome biosignatures in mice.

BACKGROUND: In the present study, we applied microarray technology to define biosignatures by microarray transcriptome analysis in lung and spleen samples after BCG vaccination and M. bovis infection of BALB/c mice. The aims were two-fold, namely to define biosignatures that could predict vaccine su...

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Bibliographic Details
Main Authors: Elihu Aranday Cortes, Daryan Kaveh, Javier Nunez-Garcia, Philip J Hogarth, H Martin Vordermeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2893133?pdf=render