CD4+ Recent Thymic Emigrants Are Recruited into Granulomas during Leishmania donovani Infection but Have Limited Capacity for Cytokine Production.

Recent thymic emigrants (RTEs) represent a source of antigen-naïve T cells that enter the periphery throughout life. However, whether RTEs contribute to the control of chronic parasitic infection and how their potential might be harnessed by therapeutic intervention is currently unclear. Here, we sh...

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Bibliographic Details
Main Authors: John W J Moore, Lynette Beattie, Mohamed Osman, Benjamin M J Owens, Najmeeyah Brown, Jane E Dalton, Asher Maroof, Paul M Kaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033337?pdf=render