Loss of heterozygosity by mitotic recombination in diploid strain of Aspergillus nidulans in response to castor oil plant detergent

Somatic recombination in heterozygous diploid cells may be a promotional agent of neoplasms by inducing homozygosity of defective genes. Tumor suppressor genes may in this way be completely suppressed in recombinant cells. In this work, the genotoxic effects of detergent derived from the castor oil...

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Bibliographic Details
Main Authors: S. A. Souza-Júnior, E. A. L. Gonçalves, S. A. Catanzaro-Guimarães, M. A. A. Castro-Prado
Format: Article
Language:English
Published: Instituto Internacional de Ecologia
Series:Brazilian Journal of Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842004000500019&lng=en&tlng=en