Antigen-Specific CD4+CD8+ Double-Positive T Cells Are Increased in the Blood and Spleen During Ehrlichia chaffeensis Infection in the Canine Host

Antigen-Specific CD4+CD8+ Double-Positive T Cells Are Increased in the Blood and Spleen During Ehrlichia chaffeensis Infection in the Canine Host

Ehrlichia chaffeensis is an obligate intracellular bacterium belonging to the order, Rickettsiales and is a frequent cause of severe and fatal tick-borne infection in people in North America. The reservoir host for E. chaffeensis is the white-tailed deer, while humans and dogs are regarded as common...

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Bibliographic Details
Main Authors: Jodi L. McGill, Ying Wang, Chanran K. Ganta, Gunavanthi D. Y. Boorgula, Roman R. Ganta
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Ehrlichia chaffeensis
Rickettsia
vaccination
immune response
double-positive T cells
tick-borne disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01585/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01585/full

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