Protective Effects of Silymarin against Cardiac Tissue Injury Caused By a High-dose Administration of Isotretinoin in Mice

Protective Effects of Silymarin against Cardiac Tissue Injury Caused By a High-dose Administration of Isotretinoin in Mice

Objective:We aimed to histopathologically and biochemically investigate the protective effects of silymarin (SLY) against cardiac injury induced by a high-dose isotretinoin (ISR) administration.Methods:Thirty-two male Balb/c mice were divided into four groups: control, ISR, SLY, and co-treated (ISR+...

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Bibliographic Details
Main Authors: Meltem KUMAŞ, Mukaddes EŞREFOĞLU, Ömer Faruk ÖZER
Format: Article
Language:English
Published: Galenos Publishing House 2016-08-01
Series:Bezmiâlem Science
Subjects:
Isotretinoin
silymarin
heart
oxidative stress
apoptosis
histopathology
Online Access: http://bezmialemscience.org/archives/archive-detail/article-preview/protective-effects-of-silymarin-against-cardiac-ti/20336

Internet

http://bezmialemscience.org/archives/archive-detail/article-preview/protective-effects-of-silymarin-against-cardiac-ti/20336

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