Multi-Spectroscopic Characterization of Human Serum Albumin Binding with Cyclobenzaprine Hydrochloride: Insights from Biophysical and <i>In Silico</i> Approaches

Multi-Spectroscopic Characterization of Human Serum Albumin Binding with Cyclobenzaprine Hydrochloride: Insights from Biophysical and <i>In Silico</i> Approaches

Cyclobenzaprine hydrochloride (CBH) is a well-known muscle relaxant that is widely used to relieve muscle spasms and other pain associated with acute musculoskeletal conditions. In this study, we elucidated the binding characteristics of this muscle relaxant to human serum albumin (HSA). From a phar...

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Bibliographic Details
Main Authors: Mohammad Hassan Baig, Safikur Rahman, Gulam Rabbani, Mohd Imran, Khurshid Ahmad, Inho Choi
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
muscle relaxant
circular dichroism
cyclobenzaprine hydrochloride
esterase-like activity
human serum albumin
molecular docking
molecular dynamics
Online Access:https://www.mdpi.com/1422-0067/20/3/662

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https://www.mdpi.com/1422-0067/20/3/662

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