Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling

Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling

Abstract Background Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors. The aim of this study was to determine potential effects of dysregulated TGFB signaling in the ovary using Cre re...

Full description

Bibliographic Details
Main Authors: Yang Gao, Xin Fang, David F. Vincent, David W. Threadgill, Laurent Bartholin, Qinglei Li
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Reproductive Biology and Endocrinology
Subjects:
TGFB
Ovary
Gdf9-iCre
Tumor
Online Access:http://link.springer.com/article/10.1186/s12958-017-0312-z

Internet

http://link.springer.com/article/10.1186/s12958-017-0312-z

Similar Items