Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome

Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome

Abstract Newcastle disease virus (NDV) infection causes severe inflammation and is a highly contagious disease in poultry. Virulent NDV strains (GM) induce large quantities of interleukin-1β (IL-1β), which is the central mediator of the inflammatory reaction. Excessive expression of IL-1β exacerbate...

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Bibliographic Details
Main Authors: Pei Gao, Libin Chen, Lei Fan, Jinlian Ren, Haoyun Du, Minhua Sun, Yaling Li, Peng Xie, Qiuyan Lin, Ming Liao, Chenggang Xu, Zhangyong Ning, Chan Ding, Bin Xiang, Tao Ren
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-020-00774-0

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http://link.springer.com/article/10.1186/s13567-020-00774-0

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