Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry

Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry

Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made available. Broad-spectrum antivirals are drugs with...

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Bibliographic Details
Main Authors: Michela Mazzon, Ana Maria Ortega-Prieto, Douglas Imrie, Christin Luft, Lena Hess, Stephanie Czieso, Joe Grove, Jessica Katy Skelton, Laura Farleigh, Joachim J. Bugert, Edward Wright, Nigel Temperton, Richard Angell, Sally Oxenford, Michael Jacobs, Robin Ketteler, Marcus Dorner, Mark Marsh
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
broad-spectrum antivirals
host-targeted antivirals
alphaviruses
flaviviruses
endocytosis
virus entry
Zika
dengue
Semliki Forest virus
phenotypic screening
Online Access:https://www.mdpi.com/1999-4915/11/2/176

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https://www.mdpi.com/1999-4915/11/2/176

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