Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation

Diabetic nephropathy, a devastating consequence of diabetes mellitus, is characterized by the accumulation of extracellular matrix (ECM) that disrupts the kidney’s filtration apparatus. Elevated glucose levels increase the deposition of a fibronectin (FN) matrix by mesangial cells, the primary matri...

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Bibliographic Details
Main Authors: Maria E. Vega, Birgit Kastberger, Bernhard Wehrle-Haller, Jean E. Schwarzbauer
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/3/655