Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer

Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer

The presence of tumor infiltrating lymphocytes (TILs) is associated with a longer overall survival in advanced stage epithelial ovarian cancer. Despite the prognostic impact of TILs, response to checkpoint-inhibitors and antigen-specific active immunotherapy is limited in ovarian cancer. The goal of...

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Bibliographic Details
Main Authors: Thaïs Baert, Ann Vankerckhoven, Matteo Riva, Anaïs Van Hoylandt, Gitte Thirion, Gerhardt Holger, Thomas Mathivet, Ignace Vergote, An Coosemans
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
ovarian cancer
immunosuppression
myeloid derived suppressor cells
adaptive immune system
innate immune system
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01273/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01273/full

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