Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experiments, the editing frequency increased at all loci wi...

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Bibliographic Details
Main Authors: Debora Fumagalli, David Gacquer, Françoise Rothé, Anne Lefort, Frederick Libert, David Brown, Naima Kheddoumi, Adam Shlien, Tomasz Konopka, Roberto Salgado, Denis Larsimont, Kornelia Polyak, Karen Willard-Gallo, Christine Desmedt, Martine Piccart, Marc Abramowicz, Peter J. Campbell, Christos Sotiriou, Vincent Detours
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715010438

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http://www.sciencedirect.com/science/article/pii/S2211124715010438

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