Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter release

Transmitter release at synapses is regulated by preceding neuronal activity, which can give rise to short-term enhancement of release like post-tetanic potentiation (PTP). Diacylglycerol (DAG) and Protein-kinase C (PKC) signaling in the nerve terminal have been widely implicated in the short-term mo...

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Bibliographic Details
Main Authors: Özgür Genç, Olexiy Kochubey, Ruud F Toonen, Matthijs Verhage, Ralf Schneggenburger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-02-01
Series:eLife
Subjects:
synaptic plasticity
transmitter release
protein kinase C
protein phosphatase
calyx of Held
synaptic transmission
Online Access:https://elifesciences.org/articles/01715

Internet

https://elifesciences.org/articles/01715

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