Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus

Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus

Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually just regarded as an apoptotic trigger. However, growing evidence points to mitochondrial factors modulating nuclear functions. Remarkably, after DNA damage, cytochrome c (Cc) int...

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Bibliographic Details
Main Authors: Katiuska González‐Arzola, Alejandra Guerra‐Castellano, Francisco Rivero‐Rodríguez, Miguel Á. Casado‐Combreras, Gonzalo Pérez‐Mejías, Antonio Díaz‐Quintana, Irene Díaz‐Moreno, Miguel A. De la Rosa
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:FEBS Open Bio
Subjects:
chromatin remodelling
cytochrome c
DNA damage response
histone chaperone
liquid–liquid phase separation
lysine acetylation
Online Access:https://doi.org/10.1002/2211-5463.13176

Internet

https://doi.org/10.1002/2211-5463.13176

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